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Midazolam BP Ph Eur USP EP IP Grade Manufacturers
Anmol Chemicals is a manufacturer supplier exporter of Midazolam BP Ph Eur USP EP IP Grade and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.
We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.
All technical documents and DMF support available.
Midazolam SDS of Manufacturers
Synonyms: Midazolam
CAS Number: 59467-70-8, Molecular Weight: 325.77, Chemical Formula: C18H13ClFN3, EINECS EC Number: 261-774-5, FEMA: NA,
Midazolam is a fast-acting, short-duration benzodiazepine. It is primarily used for procedural sedation, anesthesia induction, and seizure management. Because it induces drowsiness, relieves anxiety, and causes short-term amnesia, it is frequently administered before surgeries or minor medical procedures.
General Properties and Specifications of Midazolam:
Appearance: White or yellowish, crystalline powder.
Assay: 98.5% minimum.
Melting Point: 161C to 164C. 158C to 164C is also reported in literature.
Solubility: Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent), soluble in methanol.
Storage: Preserve in tight, light-resistant containers. Preferably refrigerate 2C to 8C.
Midazolam USP Grade Specifications:
C18H13ClFN3 --- 325.77
4-H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl;
8-Chloro-6-(o-fluorophenyl)-1-methyl-4H -imidazo[1,5-a][1,4]benzodiazepine
CAS 59467-70-8
UNII: R60L0SM5BC
DEFINITION
Midazolam contains NLT 98.5% and NMT 101.5% of C18H13ClFN3, calculated on the dried basis.
IDENTIFICATION
A. Infrared Absorption.
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution.
Residue on Ignition: NMT 0.1%
Organic Impurities; To pass the test by chromatography.
Loss on Drying: Dry a sample at 105C for 2 h: it loses NMT 0.5% of its weight.
Packaging and Storage: Preserve in tight, light-resistant containers.
Midazolam BP Ph Eur Grade Specifications:
C18H13ClFN3 --- 325.8 CAS 59467-70-8
Action and use: Benzodiazepine.
DEFINITION
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine.
Content: 98.5 per cent to 101.5 per cent (dried substance).
CHARACTERS
Appearance: White or yellowish, crystalline powder.
Solubility: Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent), soluble in methanol.
IDENTIFICATION
First identification: B
Second identification: A, C, D, E
A. Melting point: 161C to 164C.
B. Infrared absorption spectrophotometry.
C. Examine the chromatograms obtained in the test for impurity C.
D. Mix 90 mg with 0.30 g of anhydrous sodium carbonate and ignite in a crucible until an almost white residue is obtained (normally in less than 5 min). Allow to cool and dissolve the residue in 5 mL of dilute nitric acid. Filter (the filtrate is also used in identification test E). Add 1.0 mL of the filtrate to a freshly prepared mixture of 0.1 mL of alizarin S solution and 0.1 mL of zirconyl nitrate solution. Mix, allow it to stand for 5 min and compare the colour of the solution with that of a blank prepared in the same manner. The test solution is yellow, and the blank solution is red.
E. To 1 mL of the filtrate obtained in identification test D add 1 mL of water. The solution gives reaction (a) of chlorides.
TESTS
Appearance of solution: The solution is clear and not more intensely coloured than reference solution. Dissolve 0.1 g in 0.1 M hydrochloric acid and dilute to 10 mL with the same acid.
Related substances: To pass the test by Liquid chromatography.
Impurity C: To pass the test by Thin-layer chromatography.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in an oven at 105C for 2 h.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g in a platinum crucible.
Midazolam USP BP Ph Eur EP IP Grade is manufactured as per latest monograph.
Keywords: Midazolam IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade CAS Number 59467-70-8 Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.
Manufacturer Supplier Exporter
ANMOL CHEMICALS Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 65290102, +91 22 65290103
Taloja Navi Mumbai, Banglore, INDIA
e-mail: info@anmol.org
Copyright and Usual Disclaimer is Applicable
Last updated 30-may-26
Exporters to USA, Canada, UAE, Kuwait, Qatar, Gautemala, Tunisia, Europe, South Africa, Bangladesh, Sri Lanka, Tanzania, Kenya, Egypt, Iraq, Turkey, Israel, Vietnam, Nigeria, Uganda, Brazil, Chile, Argentina, Dubai, UAE, Saudi Arabia, Cameroon, Mexico, Brazil, Chile, Argentina, Korea, Thailand, Malaysia, Indonesia, Jakarta, Australia, China, Germany, France, etc.
Representatives in New York, Houston - Texas, Chicago - Illinois, Los Angeles.
All products are Sold for Industrial and Laboratory Use only.
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Midazolam
IP BP Ph Eur EP USP Grade Manufacturers