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Diphenhydramine Hydrochloride or Diphenhydramine HCl BP Ph Eur USP EP Grade Manufacturers
Anmol Chemicals is a manufacturer supplier exporter of Diphenhydramine Hydrochloride or Diphenhydramine HCl and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.
We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.
All technical documents and DMF support available.
Diphenhydramine Hydrochloride or Diphenhydramine HCl SDS of Manufacturers
Synonyms: Diphenhydramine Hydrochloride or Diphenhydramine HCl
CAS Number: 147-24-0, Molecular Weight: 291.82, Chemical Formula: C17H21NOClH, EINECS EC Number: 205-687-2, FEMA: NA,
Diphenhydraminhydrochlorid or Diphenhydramine hydrochloride is a first-generation H1-antihistamine used to treat allergies, insomnia, motion sickness, and cold symptoms.
General Properties and Specifications of Diphenhydramine Hydrochloride:
Appearance: White or almost-white crystalline powder.
Odor: Odorless.
Assay: >98%
Melting Point: 168C to 172C literature.
Solubility: Soluble in water. Soluble in Chloroform, Acetone, Alcohol.
Storage: Room Temperature (Recommended in a cool and dark place, <15°C).
Diphenhydramine Hydrochloride USP Grade Specifications:
C17H21NO-HCl --- 291.82
Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, hydrochloride;
2-(Diphenylmethoxy)-N,N-dimethylethylamine hydrochloride CAS 147-24-0
UNII: TC2D6JAD40
UNII: 8GTS82S83M
DEFINITION
Diphenhydramine Hydrochloride contains NLT 98.0% and NMT 102.0% of diphenhydramine hydrochloride (C17H21NO ·HCl), calculated on the dried basis.
IDENTIFICATION
A. Infrared Absorption
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.
C. Identification Tests—General, Chloride.
Residue on Ignition: NMT 0.1%
Organic Impurities: To pass the test by chromatography.
Acidity or Alkalinity:
Sample solution: 50 mg/mL of Diphenhydramine Hydrochloride in carbon ioxide-free water
Analysis: To 10 mL of the Sample solution, add 0.15 mL of methyl red TS 2 and 0.25 mL of 0.01 N hydrochloric acid. The solution is pink. Titrate with 0.01 N sodium hydroxide.
Acceptance criteria: ;NMT 0.5 mL of 0.01 N sodium hydroxide is required to change the color of the solution to yellow.
Loss on Drying: Dry a sample at 105C for 3 h. Loss NMT 0.5%
Packaging and Storage: Preserve in tight, light-resistant containers. Store at room temperature.
Diphenhydramine Hydrochloride BP Ph Eur Grade Specifications:
C17H22ClNO --- 291.8 CAS 147-24-0
Action and use: Histamine H1 receptor antagonist; antihistamine.
Preparations:
Diphenhydramine Oral Solution
Diphenhydramine Tablets.
DEFINITION
2-(Diphenylmethoxy)-N,N-dimethylethanamine hydrochloride.
Content: 99.0 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline powder.
Solubility: Very soluble in water, freely soluble in ethanol (96 per cent).
IDENTIFICATION
First identification: C, D
Second identification: A, B, D
A. Melting point: 168C to 172C.
B. Ultraviolet and visible absorption spectrophotometry
C. Infrared absorption spectrophotometry.
D. It gives reaction of chlorides.
Solution S: Dissolve 1.0 g in carbon dioxide-free water and dilute to 20 mL with the same solvent.
Appearance of solution: Solution S and a fivefold dilution of solution S are clear. Solution S is not more intensely coloured than reference solution.
Acidity or alkalinity: To 10 mL of solution S add 0.15 mL of methyl red solution and 0.25 mL of 0.01 M hydrochloric acid. The solution is pink. Not more than 0.5 mL of 0.01 M sodium hydroxide is required to change the colour of the indicator to yellow.
Related substances: To pass the test by Liquid chromatography.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
We also manufacture Diphenhydramine Hydrochloride as per EP Grade Monograph.
Keywords: Diphenhydramine Hydrochloride or Diphenhydramine HCl IP BP Ph Eur EP USP Analytical Reagent FCC Food Grade CAS Number 147-24-0 Manufacturer Supplier Exporter Monograph Uses Chemical Molecular Formula Weight.
Manufacturer Supplier Exporter
ANMOL CHEMICALS Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 65290102, +91 22 65290103
Taloja Navi Mumbai, Banglore, INDIA
e-mail: info@anmol.org
Copyright and Usual Disclaimer is Applicable
Last updated 31-may-26
Exporters to USA, Canada, UAE, Kuwait, Qatar, Gautemala, Tunisia, Europe, South Africa, Bangladesh, Sri Lanka, Tanzania, Kenya, Egypt, Iraq, Turkey, Israel, Vietnam, Nigeria, Uganda, Brazil, Chile, Argentina, Dubai, UAE, Saudi Arabia, Cameroon, Mexico, Brazil, Chile, Argentina, Korea, Thailand, Malaysia, Indonesia, Jakarta, Australia, China, Germany, France, etc.
Representatives in New York, Houston - Texas, Chicago - Illinois, Los Angeles.
All products are Sold for Industrial and Laboratory Use only.
Fast Selling IP BP Ph Eur EP USP NF JP Analytical Reagent FCC Food Grades of Chemicals by Anmol Chemicals
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Diphenhydramine Hydrochloride
Diphenhydramine HCl BP Ph Eur EP USP Grade Manufacturers