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for Active Substance to be imported into European Union (EU).Timolol Maleate SDS of Manufacturers
Anmol Chemicals is a manufacturer supplier exporter of Timolol Maleate and it offers materials as per IP BP EP Ph Eur USP NF JP FCC Food Grade as per the the latest monograph at best prices. Anmol Chemicals Group, established in 1976, is the pioneer manufacturer of Specialty Chemicals, Pharmaceutical Excipients, Some API, Food Chemicals in India. Anmol Chemicals Group has manufacturing facilities spread across Western India, representatives in Houston, Chicago USA and Dubai, UAE. We also have toll manufacturing units for processing chemicals in a few countries around the world. We make IP, BP, EP, USP, NF, Ph. Eur., JP, FCC or Food Grade, Analytical Reagent Grade, LR or Laboratory Reagent Grades and Pure Grades of various chemicals. All our items are analyzed to meet the required standards. We can supply the product in grams for your laboratory trial and in tons for your plant scale jobs.
We manufacture Bulk Drugs / API, Excipients, Pharmaceuticals (IP BP USP NF Ph Eur EP JP), Specialty Chemicals (Pure/Reagent), Mineral Fortifiers (FCC). Our manufacturing facility is FDA approved and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) is available. Solid materials can be customized for particle size, shape, and bulk density. We observe WHO Good Manufacturing Practices and Good Laboratory Practices. We are a government-recognized STAR Export House and "Authorised Economic Operator (AEO)" per Indian Customs.
All technical documents and DMF support available.
Timolol Maleate Specifications of Manufacturers
Synonyms: Timolol Maleate
CAS Number: 26921-17-5 or 60469-65-0, Molecular Weight: 432.49, Chemical Formula: C13H24N4O3S-C4H4O4 or C17H28N4O7S, EINECS EC Number: 248-111-5, FEMA: ----,Timolol Maleate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 18-Feb-241. Product Identification
Product Name & Other Names: Timolol Maleate.
CAS Number: 26921-17-5 or 60469-65-0
EINECS EC Number: 248-111-5
Molecular Weight: 432.49
Chemical Formula: C13H24N4O3S-C4H4O4 or C17H28N4O7S
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008Acute toxicity, Oral Category 4, H302
Reproductive toxicity Category 2, H361Labeling according to GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements
IrritantGHS Label Elements
Health HazardSignal Words: Warning
Hazard Statements:
H302: Harmful if swallowed.
H361: Suspected of damaging fertility or the unborn child.Precautionary Statements:
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash contaminated parts thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310: IF SWALLOWED: Immediately call a POSION CENTER or doctor/physician.
P314: Get medical advice/attention if you feel unwell.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P302+352: IF ON SKIN: Wash with plenty of soap and water.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P360: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P403 P404: Store in well-ventilated place. Keep container tightly closed.
P501: Dispose of contents/container in accordance with local/national regulation.Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
Xn Harmful.
Xi Irritant.
Risk Phrases:
R22 Harmful if swallowed.
R61 May cause harm to the unborn child.3. Composition/Information on Ingredients
Product Name & Other Names: Timolol Maleate.
CAS Number: 26921-17-5 or 60469-65-0
EINECS EC Number: 248-111-54. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove affected person to fresh air; if normal breathing has not returned within a few minutes after exposure, get medical attention.
Skin: Remove contaminated clothing; wash affected area with soap and water; launder contaminated clothing before reuse. Seek medical attention.
Eyes: Immediately, flush eyes for 15 minutes in clear running water while holding eyelids open; seek medical attention immediately.
Ingestion: Drink two glasses of water followed by milk, milk of magnesia or other non-alcoholic liquids; Do not induce vomiting; seek medical attention immediately.
Physician may treat symptomatically.5. Fire Fighting Measures
General Hazards: Product will support combustion.
Extinguishing Media: Carbon dioxide, water fog, dry chemical, chemical foam. Keep containers cool by spraying with water. Use extinguishing media appropriate for surrounding fire.
Fire & Explosion Hazard: May evolve oxides of carbon (COx), nitrogen oxides, sulfur oxides and fumes under fire conditions.
In case of fire, wear a full face positive-pressure self-contained breathing apparatus and protective suit. Self - contained respiratory equipment; cool containers to prevent pressure buildup and explosion when exposed to extreme heat. Caution - material will support combustion!
Unusual Fire and Explosion Hazards: Closed containers can explode due to buildup of pressure when exposed to extreme heat.
Hazardous Combustion Products: Products of combustion include nitrogen oxides, sulfur oxides, CO, CO2 and toxic fumes.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter sewer, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Vacuum or sweep up and remove to an approved disposal container.7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Keep containers closed when not in use; protect containers from abuse; protect from extreme temperatures, open flames. This material will support combustion. Room temperature. Preferably refrigerate.8. Exposure Controls/Personal Protection
Engineering Controls: The use of local exhaust ventilation is recommended to control emissions near the source. Provide mechanical ventilation of confined spaces. Use corrosion-resistant, explosion-proof ventilation equipment.
Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.9. Physical and Chemical Properties
Appearance: A white or almost white crystals or powder.
Odor: Not available.
Odor threshold: Not available.
pH: 3.8 to 4.3 in 2% solution.
Relative density: Not available.
Melting point/freezing point: 198C literature.
Boiling Point: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor Pressure (MM Hg): Not available.
Vapor Density (Air = 1): Not available.
Evaporation Rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility in Water: Soluble in water and methanol, ethanol (96%). Sparingly soluble in chloroform.
Viscosity: Not available.
Molecular Weight: 432.49
Chemical Formula: C13H24N4O3S-C4H4O4 or C17H28N4O7S10. Stability and Reactivity
Stability: Stable at recommended temperatures and operating conditions.
Conditions to Avoid: Avoid excessively high temperatures, sunlight, air, and incompatibles.
Incompatibilities: Strong oxidizing agents.
Decomposition: Decomposition yields nitrogen oxides, sulfur oxides, carbon monoxide & dioxide, fumes.
Polymerization: Polymerization will not occur.11. Toxicological Information
Reproduction: Suspected of damaging the unborn child. Suspected of damaging fertility.
Mutagenicity: Not known.
Carcinogenicity: Not listed as a human carcinogen by OSHA, IARC, ACGIH & NTP.
Acute Oral Effects: Oral LD50 Rats: 1028 mg/kg.
Acute Dermal Toxicity: LD50 Dermal Rat: 3129 mg/kg.12. Ecological Information
Toxicity to fresh-water fish: Not available.
Persistence and accumulation: Not available.
Mobility: Not available.13. Disposal Considerations
Dispose in accordance with Local, State, and Federal Regulations. Consult local, state, or Federal Environmental Protection Agency before disposing of any chemicals.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
IMDG/IMO & IATA/ICAO: Not regulated.15. Regulatory Information
UNITED STATES REGULATORY INFORMATION
SARA 311/312 Hazard Categories: See section 2 for more information.Section 16 - Additional Information
European Labeling in Accordance with EC Directives:
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
H302: Harmful if swallowed.
H361: Suspected of damaging fertility or the unborn child.
Hazard Symbols:
Xn Harmful.
Xi Irritant.
Risk Phrases:
R22 Harmful if swallowed.
R60 May impair fertility.
R61 May cause harm to the unborn child.Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Manufacturer Supplier Exporter
ANMOL CHEMICALS
Now maturing as Anmol Chemicals Private Limited
Representatives in Houston, Chicago and New York, USA
TEL: (OFF) +91 22 23726950, +91 22 23774610, +91 22 23723564
Taloja Navi Mumbai, INDIAe-mail: info@anmol.org
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Last updated 6-mar-24Exporters to USA, Canada, UAE, Kuwait, Qatar, Gautemala, Tunisia, Europe, South Africa, Bangladesh, Sri Lanka, Tanzania, Kenya, Egypt, Iraq, Turkey, Israel, Vietnam, Nigeria, Uganda, Brazil, Chile, Argentina, Dubai, UAE, Saudi Arabia, Cameroon, Mexico, Brazil, Chile, Argentina, Korea, Thailand, Malaysia, Indonesia, Jakarta, Australia, China, Germany, France, etc.
Representatives in New York, Houston - Texas, Chicago - Illinois, Los Angeles.
All products are Sold for Industrial and Laboratory Use only. No other use is permitted.
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